CSEC BIOLOGY · SECTION C · LESSON C1

DNA, Genes, Chromosomes and Mitosis

How DNA, chromosomes, genes and alleles relate; the stages of mitosis; and why asexual reproduction gives identical offspring.

Continuity and VariationSO C 1.1SO C 2.1SO C 2.2SO C 2.3≈ 30 min🎮 3 games
Before you start

By the end of this lesson you can…

Step 1 · Watch

Explainer video

6 narrated scenes. Press play, listen and read along — the points appear as they are explained. Use ‹ Prev / Next › or the scene bar to jump to any scene.

LESSON C1 · EXPLAINER

DNA, Genes, Chromosomes and Mitosis

Sugar cane fields are clones. That’s efficient — and dangerous. Here’s why.

Narration uses your device’s built-in voice. No sound? Switch to “Captions only” — the captions advance on their own.

Explore in 3D

DNA and mitosis in 3D

Unzip the DNA helix and step through mitosis.

Step 2 · Read

Key notes

Copy these into your notebook in your own words — that is how they stick.

DNA

Molecule carrying genetic information; double helix; base sequence codes for proteins.

Chromosome

Structure of DNA wrapped around histone proteins; found in the nucleus.

Gene

A length of DNA that codes for a particular protein/characteristic.

Allele

Alternative form of a gene, found at the same locus on homologous chromosomes.

Diploid/haploid

Diploid (2n) body cells; haploid (n) gametes.

Mitosis

Prophase → metaphase → anaphase → telophase; 2 identical diploid cells.

Importance of mitosis

Growth, repair, replacement of cells, asexual reproduction.

Asexual reproduction

Offspring identical because produced by mitosis from one parent — no mixing of genes.

EXAM TIPS & COMMON MISTAKES

  • Chromosome (P1) = “structure made up of DNA wrapped around histones”. Gene = part of DNA coding for a protein. Allele = two forms of the same gene.
  • Mitosis order: chromosomes appear → line up at equator → pulled apart → two nuclei.
  • Count chromosomes in the PARENT cell from the diagram at metaphase (each X = 1 chromosome).
Step 2 · Learn from examples

Worked examples & study resources

The kind of support a teacher gives after the lesson: worked examples to attempt first, a board illustration, key terms, common misconceptions and memory aids.

Worked example 1

Counting chromosomes in mitosis

A skin cell from a dog contains 78 chromosomes. It divides by mitosis.
(a) How many chromosomes will each daughter cell have? (b) How many chromatids are there in the cell at metaphase? (c) Name the stages of mitosis in order.

Try it in your notebook first, then reveal the solution one step at a time.

  1. Before mitosis, during interphase, each chromosome makes an exact copy of its DNA, so each chromosome is made of two identical chromatids.
  2. At metaphase there are still 78 chromosomes, but each has 2 chromatids: 78 × 2 = 156 chromatids.
  3. At anaphase the chromatids separate and move to opposite ends of the cell, so each new cell receives one copy of every chromosome.
  4. Each daughter cell therefore has 78 chromosomes — the same number as the parent, and genetically identical to it.
  5. Order: (interphase) → prophase → metaphase → anaphase → telophase.
Answer. (a) 78. (b) 156 chromatids. (c) Prophase, metaphase, anaphase, telophase (after interphase, when DNA is copied).
Examiner’s tip. Mitosis keeps the chromosome number the same. If an answer has the number halving, it is describing meiosis.
Worked example 2

Using the base-pairing rule

(a) One strand of DNA has the base sequence A T G C C A. Write the sequence of the matching strand. (b) A sample of DNA is 20% adenine. Calculate the percentage of guanine.

Try it in your notebook first, then reveal the solution one step at a time.

  1. The base-pairing rule: A always pairs with T, and C always pairs with G.
  2. (a) A→T, T→A, G→C, C→G, C→G, A→T, so the matching strand is T A C G G T.
  3. (b) Adenine pairs with thymine, so thymine is also 20%. A + T = 40%.
  4. That leaves 100 − 40 = 60% for guanine and cytosine, which are equal: guanine = 60 ÷ 2 = 30%.
Answer. (a) TACGGT. (b) 30% guanine.
Examiner’s tip. Because bases always pair the same way, each strand can act as a template — that is how DNA is copied exactly before mitosis.
On the board · DNA, genes and chromosomes — a recipe-book picture
TermWhat it isRecipe-book picture
DNAMolecule carrying the genetic code: a double helix with bases A–T and C–GThe letters and words
GeneA section of DNA that codes for one protein (one characteristic)One recipe
AlleleA different form of the same geneTwo versions of the same recipe
ChromosomeA long, coiled DNA molecule carrying many genesA recipe book
NucleusHolds all the chromosomes (46 in human body cells)The bookshelf

Use the analogy to remember how the terms fit inside each other — but give the scientific definition in the exam.

Key terms

DNA
Deoxyribonucleic acid — the molecule that carries genetic information.
Gene
A length of DNA that codes for a particular protein.
Allele
An alternative form of a gene.
Chromosome
A thread-like structure of DNA, found in the nucleus.
Chromatid
One of the two identical copies of a chromosome after DNA replication.
Diploid (2n)
Having two sets of chromosomes, e.g. 46 in human body cells.
Mitosis
Cell division producing two genetically identical cells with the same chromosome number.

Common misconceptions

  • ✗ Mitosis halves the number of chromosomes.✓ Mitosis keeps the number the same. Meiosis halves it.
  • ✗ A gene and an allele are the same thing.✓ A gene is for a characteristic (e.g. height); alleles are its different versions (tall, short).
  • ✗ More complex organisms have more chromosomes.✓ Chromosome number is not linked to complexity: humans have 46, dogs 78, some ferns over a thousand.

Memory aid

Stages of mitosis: I Prefer My Apple Tart — Interphase, Prophase, Metaphase, Anaphase, Telophase.

Real-life link

Caribbean farmers grow sugar cane from stem cuttings (setts), bananas from suckers and pineapples from crowns. Every new plant is produced by mitosis, so it is a genetically identical clone of the parent.

Try this

Model mitosis with two colours of string or pipe cleaners: make 2 pairs of “chromosomes”, copy each one, line them up in the middle, and pull the copies apart into two new “cells”.

Play & practise

Games

3 quick games on this lesson. Earn XP and badges as you play — your best score for each game is saved. Games are for practice and do not change your exam readiness.

Step 3 · Practise

Paper 1 practice — multiple choice

8 items modelled on real CSEC Paper 1 questions. Choose one answer for each, then check. Aim for 80% or better.

Adapted from CSEC P1 2022 Item 50; 2023 Item 51; 2024 Item 50

1. Which BEST describes a chromosome?

Answer: A. “Two forms of the same gene” describes alleles; “part of the DNA coding for a protein” describes a gene.
Adapted from CSEC P1 May/June 2024, Item 58

2. As a result of mitosis, each daughter cell has

Answer: C. Mitosis keeps the chromosome number.
Adapted from CSEC P1 2022 Item 51; 2023 Item 52

3. Stages of mitosis: I chromatids pulled to poles; II chromosomes on equator; III chromosomes visible in nucleus; IV two nuclei forming. The correct order is

Answer: C. Prophase → metaphase → anaphase → telophase.
Based on CSEC P2 January 2022, Q4(c)

4. Sugar cane is propagated from stem cuttings. The type of cell division involved is

Answer: B. Vegetative propagation relies on mitosis.
Adapted from CSEC P1 2022 Item 52; 2023 Item 53; 2024 Item 52

5. A fungus destroyed an entire sugar-cane crop on an island. The BEST explanation is that

Answer: B. Clones share the same susceptibility.
EduTech practice item (SO C1.1)

6. An alternative form of a gene is called

Answer: D. Alleles are versions of one gene.
EduTech practice item

7. Human gametes are haploid. They contain

Answer: D. n = 23 in humans.
EduTech practice item

8. Which is NOT a function of mitosis?

Answer: A. Human gametes are made by meiosis.
Step 4 · Apply

Paper 2 practice — structured questions

Write full answers, then reveal the mark scheme and tick the points you earned (16 marks in total). Your answers are saved on this device.

Based on CSEC P2 May/June 2024, Question 2(a) and January 2024 Q5(a)

Question 1 [10 marks]

Randomly placed diagrams A–E show stages of mitosis in a plant cell; the metaphase cell shows four chromosomes on the equator.

(a) Define gene, allele and chromosome. [3]

MARK SCHEME — (a) (max 3)

(b) How many chromosomes were in the parent cell? State the correct order of stages as prophase → metaphase → anaphase → telophase and describe each. [5]

MARK SCHEME — (b) (max 5)

(c) State TWO reasons why mitosis is important to living organisms. [2]

MARK SCHEME — (c) (max 2)

Based on CSEC P2 January 2022, Question 4(c) and January 2026 Q4(c)

Question 2 [6 marks]

Sugar cane was once of great economic importance in the Caribbean.

(a) Name the type of cell division that leads to the propagation of sugar cane, and give TWO reasons explaining how it does so. [3]

MARK SCHEME — (a) (max 3)

(b) Explain why the offspring of asexual reproduction are genetically identical, and ONE disadvantage of this. [3]

MARK SCHEME — (b) (max 3)

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Sources

Where this topic appears in CSEC papers

Find these in your own past-paper booklets for extra timed practice. The practice above is adapted from them.